Briefly describes the emerging clinical evidence of effectiveness of molnupiravir and the supporting animal evidence.
Introduction Emergency hospital systems are expected to respond effectively to intentional or accidental mass casualty incidents (MCI). Such incidents are largely unpredictable, and increasing worldwide.1-3 Mitigation of the harms associated with these disasters often requires appropriate high-quality healthcare processes to be enacted rapidly, safely and without duplication or error.4 To prepare clinicians and health systems, effective training and rehearsal using the multi-systems involved in an actual response is necessary. Response frameworks (for example, Homeland Security Exercise and Evaluation Program,5 Disaster
The authors describe a case of psoriasis complicated by periodontitis and discuss the relationship between the two conditions.
The authors have documented acute analgesic treatment of 137 patients who presented with upper limb fracture while in the Emergency Department and on discharge. Opioid agents were prescribed in 55% of patients in ED and 32% on discharge.
Detailed follow-up of 24 patients with Adult-onset Still’s Disease has confirmed disease chronicity but demonstrated complete or partial responses to biological Disease-modifying drugs (BDMARDs) and the prognostic significance of hyperferritinaemia.
Australia’s contribution to the global research output into Artificial Intelligence in medicine has been measured. Most (65%) of the output came from 5 countries (USA, China, UK, Germany and Canada). Australia contributed 3.5% of the total but was second only to Canada on a population basis.
The authors have measured skin thickness in patients with scleroderma and compared the results with the current standard clinical measure, the modified Rodnan Skin Score (mRSS). Though US had satisfactory reliability and reproducibility, and detected changes in skin thickness over time, it did not correlate well with the mRSS, for reasons that remain uncertain.
Clinical and epidemiological research is often conducted using data from hospital discharge coding. The authors have studied the accuracy of a discharge coding diagnosis of gout, compared to clinical diagnoses based on ACR/EULAR 2015 gout classification criteria and case note review. The coding diagnosis was not supported by the former in over half the cases, or by the latter in almost one third.
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